| 摘要 |
A therapeutic method is provided comprising treating a mammal subject to hypoxia with an amount of 2(R,S)-D-ribo-(1′,2′,3′,4′-tetrahydroxybutyl)thiazolidine-4(R)-carboxylic acid (RibCys) or a pharmaceutically acceptable salt thereof effective to both maintain, restore or increase both the ATP levels and the glutathione (GSH) levels in said tissue. |
| 主权项 |
1. A method of treating a tissue ischemia resulting from a surgical procedure in a mammal in need thereof by increasing glutathione and ATP comprising administering an effective amount of 2(R,S)-D-ribo-(1′,2′,3′,4′-tetrahydroxybutyl)thiazolidone-4(R)-carboxylic acid, or a pharmaceutically acceptable salt thereof, to said mammal, wherein said 2(R,S)-D-ribo-(1′,2′,3′,4′-tetrahydroxybutyl)thiazolidone-4(R)-carboxylic acid increases glutathione and ATP to treat said tissue ischemia resulting from the surgical procedure. |
