主权项 |
1. A compound of Formula (I): and pharmaceutically acceptable salts, solvates, or solvates of salts, wherein: R1 is Hal, LA, OH, O(LA), NH2 and/or NH(LA), N(LA)2, NO2, CN, OCN, SCN, COOH, COO(LA), CONH2, CONH(LA), CON(LA)2, NHCO(LA), NHCONH(LA), NHCONH2, NHSO2(LA), CHO, CO(LA), SO2NH2, SO2 (LA), or a mono- or bicyclic, aliphatic or aromatic homo- or heterocycle having 0, 1, 2, 3 or 4 N, S and/or O atoms and 4, 5 or 6, 7, 8, 9, or 10 skeleton atoms which may be unsubstituted or, independently of one another, mono-, di- or trisubstituted by Hal, LA, OH, O(LA), NH2 and/or NH(LA), N(LA)2, NO2, CN, OCN, SCN, COOH, COO(LA), CONH2, CONH(LA), CON(LA)2, NHCO(LA), NHCONH(LA), NHCONH2, NHSO2(LA), CHO, CO(LA), SO2NH2, SO2 (LA) and/or SO2Hal or an unbranched or branched linear or cyclic alkyl having 1, 2, 3 , 4, 5, 6, 7 or 8 C atoms, in which one or two CH2 groups may be replaced by an O atom and/or by an —NH—, NH(LA), —CO—, —NHCO— or —CH═CH— group, and/or in which a CH group may be replaced by —N—; R2 is H, NH2, NH(LA), N(LA)2 or NHCO(LA); R3 is N or CH; R4 is H, an unbranched or branched linear or mono- or bicyclic alkyl group having 1, 2, 3, 4, 5, 6, 7, 8 or 9 C atoms, in which one or two CH2 groups may be replaced by an —O—,—NH—, group, and/or in which one or two CH groups may be replaced by —N—,
and/or in which 1, 2 or 3 H atoms may be replaced by Hal or OH, R5 is a monocyclic aromatic or aliphatic homo- or heterocycle having 0, 1 or 2 N, S and/or O atoms and 5 or 6 skeleton atoms which may be unsubstituted or, independently of one another, mono-, di- or trisubstituted by Hal, LA, OH, O(LA), NH2 and/or NH(LA), N(LA)2, NO2, CN, OCN, SCN, COOH, COO(LA), CONH2, CONH(LA), CON(LA)2, NHCO(LA), NHCONH(LA), NHCONH2, NHSO2(LA), CHO, CO(LA), SO2NH2, SO2(LA); Hal is F, CI, Br or I, and LA is an unbranched or branched, saturated or partially unstaturated, linear hydrocarbon chain having 1, 2, 3 or 4 C atoms, wherein 1, 2 or 3 H atoms may be replaced by Hal. |