发明名称 RAPAMYCIN FOR THE TREATMENT OF LYMPHANGIOLEIOMYOMATOSIS
摘要 The present invention relates to methods and compositions for treating lymphangioleiomyomatosis in a human subject in need of such treatment. The methods comprise administering to the subject via inhalation an aerosol composition comprising rapamycin or a prodrug or derivative (including analog) thereof.
申请公布号 US2015265582(A1) 申请公布日期 2015.09.24
申请号 US201514618621 申请日期 2015.02.10
申请人 LAM Therapeutics, Inc. 发明人 Armer Thomas;Melvin, JR. Lawrence S.;Rothberg Jonathan M.;Lichenstein Henri
分类号 A61K31/436;A61M15/00;A61K45/06;A61K9/00;A61K9/14 主分类号 A61K31/436
代理机构 代理人
主权项 1. A pharmaceutical aerosol formulation in the form of a dry powder for pulmonary delivery comprising an amount of microparticles of a rapamycin composition, particles of a carrier, and one or more optional excipients, wherein the formulation is effective to deliver a therapeutic amount of the rapamycin composition to the lungs.
地址 Guilford CT US