发明名称 |
RAPAMYCIN FOR THE TREATMENT OF LYMPHANGIOLEIOMYOMATOSIS |
摘要 |
The present invention relates to methods and compositions for treating lymphangioleiomyomatosis in a human subject in need of such treatment. The methods comprise administering to the subject via inhalation an aerosol composition comprising rapamycin or a prodrug or derivative (including analog) thereof. |
申请公布号 |
US2015265582(A1) |
申请公布日期 |
2015.09.24 |
申请号 |
US201514618621 |
申请日期 |
2015.02.10 |
申请人 |
LAM Therapeutics, Inc. |
发明人 |
Armer Thomas;Melvin, JR. Lawrence S.;Rothberg Jonathan M.;Lichenstein Henri |
分类号 |
A61K31/436;A61M15/00;A61K45/06;A61K9/00;A61K9/14 |
主分类号 |
A61K31/436 |
代理机构 |
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代理人 |
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主权项 |
1. A pharmaceutical aerosol formulation in the form of a dry powder for pulmonary delivery comprising an amount of microparticles of a rapamycin composition, particles of a carrier, and one or more optional excipients, wherein the formulation is effective to deliver a therapeutic amount of the rapamycin composition to the lungs. |
地址 |
Guilford CT US |