| 摘要 |
The present invention relates to medical articles, such as wound dressings, and in particular to the use of compositions comprising a mixture of an amphiphilic co-polymer and a silicone matrix material in the formation of wound contact surfaces for wound dressings. The amphiphilic co-polymer allows a hydrophilic agent, such as a hydrophilic antimicrobial agent, to be loaded into and encapsulated within particles/micelles of the amphiphilic co-polymer, so that the hydrophilic agent can be delivered over time to a wound site when the wound contact surface of a wound dressing, which contains the agent-encapsulated particulate composition, is in contact with the wound. As such, wound infections can be readily treated by hydrophilic agents which would otherwise not be deliverable from the wound contact surface itself. |
