| 发明名称 |
INHIBITION OF INTERLEUKIN-8 AND/OR ITS RECEPTOR CXCR1 IN THE TREATMENT OF HER2/HER3-OVEREXPRESSING BREAST CANCER |
| 摘要 |
The present invention relates to a method for treating breast cancer in a subject having a breast cancer characterized by activation of the HER2/HER3 heterodimer, which method comprises the step of administering to said subject a therapeutically effective amount of a modulator of interleukin 8 (IL8) and/or of its receptor chemokine (C-X-C motif) receptor 1 (CXCR1). |
| 申请公布号 |
US2015266961(A1) |
申请公布日期 |
2015.09.24 |
| 申请号 |
US201314387602 |
申请日期 |
2013.03.27 |
| 申请人 |
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
Bentires-Alj Mohamed;Aceto Nicola |
| 分类号 |
C07K16/28;C07K16/24 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method for treating breast cancer in a subject having a breast cancer characterized by activation of the HER2/HER3 heterodimer, which method comprises the step of administering to said subject a therapeutically effective amount of a modulator of interleukin 8 (IL8) or of its receptor chemokine (C-X-C motif) receptor 1 (CXCR1). |
| 地址 |
Basel CH |
