发明名称 NOVEL EPITOPE OF IP-10 AND ANTIBODY TO SAME
摘要 The present invention relates to a novel epitope of IP-10 (IFN-γ-inducible protein 10), to an antibody to the epitope or an antigen-binding fragment thereof, to a composition comprising the epitope as an active ingredient for inducing an antibody to IP-10, and to a pharmaceutical composition comprising the antibody or the antigen-binding fragment thereof for preventing or treating diseases relating to IP-10. The anti-IP-10 antibody of the present invention can be effectively used in preventing or treating various diseases relating to IP-10 such as multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus.
申请公布号 US2015266951(A1) 申请公布日期 2015.09.24
申请号 US201314428301 申请日期 2013.09.17
申请人 SNU R&DB FOUNDATION 发明人 Song Yeong Wook
分类号 C07K16/24;C07K14/52 主分类号 C07K16/24
代理机构 代理人
主权项 1. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 5 or the amino acid sequence from 1th to 20th amino acids of SEQ ID NO: 5, wherein the polypeptide is an epitope of Interferon-γ-inducible protein 10.
地址 Seoul KR