| 发明名称 |
USE OF THE AMINOALKYLINDOLE JWH-073-M4 AND RELATED COMPOUNDS AS NEUTRAL CB1 RECPTOR ANTAGONISTS FOR THE TREATMENT OF ALCOHOLISM, DRUG ABUSE, OBESITY, AND OBESITY-RELATED DISEASES |
| 摘要 |
Novel alkylindoles that bind tightly to cannabinoid receptors and are neutral antagonists for the cannabinoid 1 receptor and agonists for the cannabinoid 2 receptor are provided. These compounds are useful for treating alcoholism and drug abuse and for treating obesity. |
| 申请公布号 |
US2015266820(A1) |
申请公布日期 |
2015.09.24 |
| 申请号 |
US201314370951 |
申请日期 |
2013.01.08 |
| 申请人 |
The Board of Trustees of the University of Arkansas ;The University of Kansas |
发明人 |
Prather Paul L.;Prisinzano Thomas E.;Fantegrossi William E.;Brents Lisa K.;Moran Jefferey;Radominska-Pandya Anna;Vasiljevik Tamara |
| 分类号 |
C07D209/08;A61K49/00;G01N33/49 |
主分类号 |
C07D209/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising a compound of formula III: wherein R1 is 5-O-methyl, 7-O-methyl, or 7-OH; R2 is C1-C6 linear alkyl; and R3 is |
| 地址 |
Little Rock AR US |
