发明名称 |
METHOD OF OVERCOMING THERAPEUTIC LIMITATIONS OF NONUNIFORM DISTRIBUTION OF RADIOPHARMACEUTICALS AND CHEMOTHERAPY DRUGS |
摘要 |
Disclosed is a method for predicting the optimal amounts of radiopharmaceutical and/or chemotherapy agents to administer to a patient, by determining the level of saturation of the therapeutic agents in the patient's cells. The method comprises measuring cellular incorporation of the candidate therapeutic agents in a target cell population on a cell-by-cell basis. The method is able to identify an optimal cocktail of therapeutic agents for treatment of a disease. A method of high-throughput drug discovery incorporating this method, and a 2-stage targeting method of treating a disease using this method are also disclosed. |
申请公布号 |
US2015265730(A1) |
申请公布日期 |
2015.09.24 |
申请号 |
US201414526041 |
申请日期 |
2014.10.28 |
申请人 |
Rutgers, The State University of New Jersey |
发明人 |
Akudugu John M.;Neti Venkata S.;Howell Roger W. |
分类号 |
A61K51/04;A61K31/704 |
主分类号 |
A61K51/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
New Brunswick NJ US |