| 发明名称 |
VACCINE COMPOSITIONS FOR PREVENTION AGAINST DENGUE VIRUS INFECTION |
| 摘要 |
The present invention relates to vaccine compositions that are useful in a method of protecting a human subject against dengue disease. |
| 申请公布号 |
US2015265695(A1) |
申请公布日期 |
2015.09.24 |
| 申请号 |
US201314416492 |
申请日期 |
2013.07.24 |
| 申请人 |
Sanofi Pasteur |
发明人 |
Yao Jiansheng;Girerd-Chambaz Yves;Legastelois Isabelle;Mantel Nathalie;Barban Véronique;Lang Jean;Guy Bruno |
| 分类号 |
A61K39/12;C12N7/00 |
主分类号 |
A61K39/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A dengue virus serotype 2 vaccine composition comprising:
(i) a dengue antigen selected from the group consisting of:
(a) a live attenuated dengue virus;(b) an inactivated dengue virus;(c) a live attenuated or inactivated chimeric dengue virus;(d) a dengue virus-like particle (VLP); and(e) a combination of two or more of (a) to (d); or (iii) a nucleic acid construct or viral vector which is able to express in a human cell a dengue antigen which is a dengue VLP;wherein said dengue antigen comprises a polypeptide having at least 90% identity to SEQ ID NO: 12. |
| 地址 |
Lyon Cedex 07 FR |
