发明名称 |
NANOSUSPENSION OF A POORLY SOLUBLE DRUG VIA MICROFLUIDIZATION PROCESS |
摘要 |
Provided are compositions and methods for preparation and administration of an oral nanosuspension of a poorly soluble drug with improved bioavailability. The method is optimized through microfluidization process with water soluble polymeric excipients in the absence of surfactants. |
申请公布号 |
US2015265534(A1) |
申请公布日期 |
2015.09.24 |
申请号 |
US201514676709 |
申请日期 |
2015.04.01 |
申请人 |
Celgene Corporation |
发明人 |
CHEN Ming J.;HUI Ho-Wah;LEE Thomas;KURTULIK Paul;SURAPANENI Sekhar |
分类号 |
A61K9/107;A61K47/20;A61K47/38;A61K47/22;A61K9/00;A61K31/4035 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Summit NJ US |