发明名称 |
AEROSOL COMPOSITION FOR ADMINISTERING DRUGS |
摘要 |
Described here are compositions and methods for the treatment of respiratory conditions using glucocorticosteroids delivered by a next generation nebulizer. The methods administer a therapeutic dose with nebulization time of 2 minutes or less. The faster nebulization time improves patient compliance. |
申请公布号 |
US2015265531(A1) |
申请公布日期 |
2015.09.24 |
申请号 |
US201514728203 |
申请日期 |
2015.06.02 |
申请人 |
MAP Pharmaceuticals, Inc. |
发明人 |
Wu Libo;Watanabe Wiwik |
分类号 |
A61K9/00;A61K9/14;A61K47/26;A61K31/58 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
1. An aqueous dispersion or suspension of a drug wherein when a therapeutic dose is administered by a next generation nebulizer to generate an inhaled aerosol composition:
said aerosol composition comprises drug particles having a mean diameter from about 1 micron to about 3 microns; said aerosol composition has a fine particle fraction of at least about 25% to about 33.8%; the nebulization time is in the range of about 15 seconds to about 120 seconds; and about 39% or less of the drug particles are retained on the mesh after the nebulization time. |
地址 |
Irvine CA US |