| 发明名称 |
キメラ抗体および処置におけるその使用 |
| 摘要 |
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases. |
| 申请公布号 |
JP5781571(B2) |
申请公布日期 |
2015.09.24 |
| 申请号 |
JP20130165247 |
申请日期 |
2013.08.08 |
| 申请人 |
ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム |
发明人 |
フィリップ イー． ソープ;メリナ エム． ソーズ;シャンミン フアン;ヒー ジン;ソフィア ラン |
| 分类号 |
A61K45/00;C07K16/30;A61K9/127;A61K39/395;A61K47/48;A61P3/04;A61P3/10;A61P5/14;A61P5/16;A61P7/04;A61P7/06;A61P9/00;A61P9/10;A61P15/08;A61P17/00;A61P17/06;A61P17/10;A61P19/02;A61P19/06;A61P27/02;A61P27/06;A61P29/00;A61P31/10;A61P31/12;A61P31/22;A61P33/00;A61P35/00;A61P37/02;A61P43/00;C07K16/18;C07K16/28;C07K16/44;C07K16/46 |
主分类号 |
A61K45/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
