FLUID FLOWING DEVICE AND METHOD FOR TISSUE DIAGNOSIS OR THERAPY

摘要

A device and method for safely securing a multilumen device to a tissue, organ or solid tumor within the body of a human during a diagnostic or therapeutic procedure is described. The device is capable of securing the tumor by touching or piercing its surface and providing a coolant to the distal tip. Cooling the tip forms a cryogenically induced region that tightly binds the tip to the tumor, temporarily sealing the entry-track of the instrument. The device further provides at least one injecting/aspirating lumen that can dispense or aspirate a fluid within the tumor, and an outer sheath or guide. Such construction allows injecting part or whole volume of the tumor while the cryogenically induced bond prevents back-flow of the injected substances through the entry-track.

主权项

1. A process for controllably delivering a treating composition to a tissue structure along an entry track comprising:
providing a backflow limiting device, said device having a multilumen catheter including at least one lumen for supply of a cryogenic material, said lumen in fluid connection with at least one cryogenic element effective for lowering at least a portion of said tissue structure to a temperature within the range of at or about the tissue freezing point, and at least one lumen for providing said at least one treating composition to an interstitial space within said tissue structure positioned distally from said at least one lumen for supply of a cryogenic material, and an outer sheath member coaxially aligned with said multilumen catheter; said multilumen catheter being constructed and arranged for injecting said at least one treating composition to a treatment region within said tissue structure in conjunction with supply of said cryogenic material; positioning said backflow limiting device within or proximate to said tissue treatment region; securing said backflow limiting device to said tissue structure by delivering cryogenic agent to a portion of said multilumen catheter lumen, whereby at least one cryogenically induced region is formed proximal to a point of delivery of said treating composition and which is effective to minimize or prevent backflow of said treating composition; maintaining said cryogenically induced region; and delivering said treating composition to said treatment region within said tissue structure by injection; whereby backflow of said treating composition through an entry track is prevented.