发明名称 Specific sites for modifying antibodies to make immunoconjugates
摘要 The present invention provides specific sites for modifying antibodies or antibody fragments by replacing at least one native amino acid in the constant region of a parental antibody or antibody fragment with cysteine, which can be used as a site of attachment for a payload or linker-payload combination.
申请公布号 IL240406(D0) 申请公布日期 2015.09.24
申请号 IL20150240406 申请日期 2015.08.06
申请人 IRM LLC;NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. 发明人
分类号 C07K 主分类号 C07K
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