发明名称 |
Estrogen receptor inhibitors |
摘要 |
<p>A method of treating ERαpositive cancer comprising administering to a patient in need thereof an effective amount of a small molecule inhibitor or a pharmaceutically acceptable salt thereof, wherein the small molecule inhibitor acts through estrogen receptor a and activates one or more of the three arms of the unfolded protein response pathway (UPR) is provided.</p> |
申请公布号 |
IL240019(D0) |
申请公布日期 |
2015.09.24 |
申请号 |
IL20150240019 |
申请日期 |
2015.07.19 |
申请人 |
DAVID J. SHAPIRO;DAVID J. SHAPIRO;NEAL D. ANDRUSKA;NEAL D. ANDRUSKA;MATHEW M. CHERIAN;MATHEW M. CHERIAN;LILY MAHAPATRA;LILY MAHAPATRA;MAO CHENGJIAN;MAO CHENGJIAN;WILLIAM HELFERICH;WILLIAM HELFERICH;XUJUAN YANG;XUJUAN YANG;XIAOBIN ZHENG;XIAOBIN ZHENG |
发明人 |
|
分类号 |
A61K |
主分类号 |
A61K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|