| 发明名称 |
VL ANTIGEN BINDING PROTEINS EXHIBITING DISTINCT BINDING CHARACTERISTICS |
| 摘要 |
Methods for making, identifying, isolating and/or making binding proteins that contain an immunoglobulin light chain variable domain, including a somatically hypermutated light chain variable domain, fused with a heavy chain constant region, are provided. Exemplary binding proteins specific to small molecules are also provided. |
| 申请公布号 |
US2015266976(A1) |
申请公布日期 |
2015.09.24 |
| 申请号 |
US201514664750 |
申请日期 |
2015.03.20 |
| 申请人 |
Regeneron Pharmaceuticals, Inc. |
发明人 |
Babb Robert;Rafique Ashique;Huang Tammy T.;Shi Ergang;Macdonald Lynn;Murphy Andrew J. |
| 分类号 |
C07K16/44;G01N33/68;A01K67/027 |
主分类号 |
C07K16/44 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An antigen-binding protein comprising a first and a second immunoglobulin light chain variable domains, wherein the first and the second immunoglobulin light chain variable domains are associated to form a binding pocket that specifically binds a small molecule. |
| 地址 |
Tarrytown NY US |
