发明名称 |
METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY |
摘要 |
Provided herein are methods and compositions related to a retinoid receptor-selective pathway. As described herein, this pathway can be targeted to manipulate a tumor microenvironment. For example, the methods and compositions described herein can be used to induce apoptosis in a cancer cell. Further, the compositions described herein, including Sulindac and analogs thereof, can be used to target this pathway for the treatment or prevention of cancer in human patients. |
申请公布号 |
US2015266842(A1) |
申请公布日期 |
2015.09.24 |
申请号 |
US201113102475 |
申请日期 |
2011.05.06 |
申请人 |
Zhang Xiao-kun;Su Ying;Zhou Hu;Liu Wen;Huang Pei-Qiang |
发明人 |
Zhang Xiao-kun;Su Ying;Zhou Hu;Liu Wen;Huang Pei-Qiang |
分类号 |
C07D295/112;C07D213/55;C07C255/57;C07C57/62;C07C59/72 |
主分类号 |
C07D295/112 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
San Diego CA US |