| 发明名称 |
FUMARATE-CO-RELEASING MOLECULE HYBRIDS, THEIR USE IN THE TREATMENT OF INFLAMMATORY OR CARDIOVASCULAR DISEASES AND THEIR PROCESS OF PREPARATION |
| 摘要 |
The present invention relates to hybrid fumarate-CO-releasing molecules capable of increasing heme oxygenase-1 (HO-1) activity and HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic applications, in particular their use in the treatment of inflammatory or cardiovascular diseases. |
| 申请公布号 |
CA2943010(A1) |
申请公布日期 |
2015.09.24 |
| 申请号 |
CA20152943010 |
申请日期 |
2015.03.20 |
| 申请人 |
UNIVERSITE PARIS EST CRETEIL VAL DE MARNE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
MOTTERLINI, ROBERTO;FORESTI, ROBERTA;MARTENS, THIERRY;RIVARD, MICHAEL |
| 分类号 |
C07F13/00;A61K31/28;A61K33/24;A61K33/32;A61P9/00;A61P29/00;C07F15/00;C07F15/06 |
主分类号 |
C07F13/00 |
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