| 发明名称 |
MONOBACTAM ORGANIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS |
| 摘要 |
This invention pertains generally to antibacterial compounds of Formula I,;;as further described herein, and pharmaceutically acceptable salts and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds to treat infections such as those caused by Gram-negative bacteria. |
| 申请公布号 |
US2015266867(A1) |
申请公布日期 |
2015.09.24 |
| 申请号 |
US201514665245 |
申请日期 |
2015.03.23 |
| 申请人 |
AULAKH Virender Singh;CASAREZ Anthony;LIN Xiaodong;LINDVALL Mika;MCENROE Glenn;MOSER Heinz Ernst;RECK Folkert;TJANDRA Meiliana;SIMMONS Robert Lowell;YIFRU Aregahegn;ZHU Qingming |
发明人 |
AULAKH Virender Singh;CASAREZ Anthony;LIN Xiaodong;LINDVALL Mika;MCENROE Glenn;MOSER Heinz Ernst;RECK Folkert;TJANDRA Meiliana;SIMMONS Robert Lowell;YIFRU Aregahegn;ZHU Qingming |
| 分类号 |
C07D417/14;A61K31/454;A61K31/4439;A61K45/06;A61K31/496;A61K31/4545;C07D487/04;A61K31/427;A61K31/433 |
主分类号 |
C07D417/14 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of Formula (IA): or a pharmaceutically acceptable salt thereof,
wherein:
Z is CH;the group —O—CR1R2R3 is selected fromand
Het is selected from |
| 地址 |
Whitehorse CA |
