发明名称 |
HETEROARYL SYK INHIBITORS |
摘要 |
The invention relates to new substituted heteroaryls of formula (1), wherein A is selected from the group consisting of N and CH, D is CH, E is selected from the group consisting of C and N, T is C, G is selected from the group consisting of C and N, and wherein each of the broken (dotted) double bonds in ring 1 are selected from either a single bond or a double bond under the proviso that all single and double bonds of ring 1 are arranged in such a way that they all form together with ring 2 an aromatic ring system, and wherein R1, M and R3 are defined according to claim 1, and to the above compounds for the treatment of a disease selected from the group consisting of asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes,lupus nephritisand rheumatoid arthritis. |
申请公布号 |
CA2942997(A1) |
申请公布日期 |
2015.09.24 |
申请号 |
CA20152942997 |
申请日期 |
2015.03.12 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
DAHMANN, GEORG;HOFFMANN, MATTHIAS;KLICIC, JASNA;LAMB, DAVID JAMES;MCCARTHY, CLIVE;NAPIER, SPENCER;PARRISH, KAREN;SCOTT, JOHN;SWANTEK FITZGERALD, JENNIFER L.;WALKER, EDWARD |
分类号 |
C07D413/12;A61K31/505;A61P11/06;C07D417/12;C07D498/04;C07D513/04 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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