PREBIOTIC EFFECT OF SIALYLLACTOSE

摘要

Provided herein are prebiotic compositions comprising a combination of oligosaccharides such as sialyated oligosaccharides and fusocylated oligosaccharides, and uses thereof in stimulating the proliferation of beneficial intestinal micro biota, for example, of bifidobacteria, and/or in decreasing the abundance of enteric pathogens. The prebiotic compositions can further contain a probiotic, which can be a population of bifidobacteria, lactobacilli, Bacteriodes fragilis, Bacteriodes thetaiotaomicron, Enterococcus faecalis (pro biotic strains thereof), Staphylococcus epidermides, Enterobacter aerogenes, Enterobacter cloacae, or related bacteria having similar functions.

主权项

1. A prebiotic composition consisting essentially of a sialyllactose and a fucosylated oligosaccharide, wherein the sialyllactose is 3′-sialyllactose (3′-SL), 6′-sialyllactose (6′-SL), or a mixture thereof, and wherein the fucosylated oligosaccharide comprises an α1,2-fucosyl, an α1,3-fucosyl, and/or an α1,4-fucosyl residue.