发明名称 |
COMPOSITIONS AND METHODS OF USE FOR THERAPEUTIC ANTIBODIES |
摘要 |
<p>The present invention relates to antibodies that specifically bind to the BAFF receptor (BAFFR). The invention more specifically relates to specific antibodies that are BAFFR antagonists with in vivo B cell depleting activity and compositions and methods of use for said antibodies to treat pathological disorders that can be treated by killing or depleting B cells, such as systemic lupus erythematosus or rheumatoid arthritis or other autoimmune diseases or lymphomas, leukemias and myelomas.</p> |
申请公布号 |
EP2315780(B8) |
申请公布日期 |
2015.09.23 |
申请号 |
EP20090797499 |
申请日期 |
2009.07.15 |
申请人 |
NOVARTIS AG |
发明人 |
HEUSSER, CHRISTOPH;NEUGEBAUER, JULIA;SCHAADT, EVELINE;URLINGER, STEFANIE;WOISETSCHLAEGER, MAXIMILIAN |
分类号 |
C07K16/28;A61K39/395;A61P19/02;A61P37/06 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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