| 摘要 |
The present invention relates to 2′-Alkynyl Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R1, R2, R3 and R4 are as defined herein. The present invention also relates to compositions comprising at least one 2′-Alkynyl Substituted Nucleoside Derivative, and methods of using the 2′-Alkynyl Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient. |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
BENNETT, FRANK;HUANG, YUHUA;WANG, LINGYAN;BOGEN, STEPHANE, L.;KEREKES, ANGELA, D.;GIRIJAVALLABHAN, VINAY M.;BUTORA, GABOR;TRUONG, QUANG;DAVIES, IAN;WEBER, ANNE E. |
