发明名称 |
CRISPR-CAS SYSTEMS AND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS |
摘要 |
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system. |
申请公布号 |
KR20150107739(A) |
申请公布日期 |
2015.09.23 |
申请号 |
KR20157018654 |
申请日期 |
2013.12.12 |
申请人 |
THE BROAD INSTITUTE, INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
ZHANG FENG |
分类号 |
C12N15/63;A61K38/46;A61K48/00;C12N9/22;C12N15/10;C12N15/85;C12N15/90 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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