发明名称 |
PURIFICATION OF POSACONAZOLE AND POSACONAZOLE INTERMEDIATES |
摘要 |
<p>The present invention relates to a process for the preparation of a hydrogen chloride (HCl) salt of a compound of formula (I) wherein Y1 and Y2 are independently F or Cl, preferably F, said compound of formula (I) containing the cis-isomer and the trans-isomer, wherein the process comprises (1) providing the compound of formula (I) comprised in a first suitable solvent; and (2) treating the compound of formula (I) comprised in the first suitable solvent with HCl comprised in a second suitable solvent to obtain the HCl salt of the compound of formula (I).</p> |
申请公布号 |
EP2571869(B1) |
申请公布日期 |
2015.09.23 |
申请号 |
EP20110720109 |
申请日期 |
2011.05.18 |
申请人 |
SANDOZ AG |
发明人 |
LANGNER, MARTIN;DE SOUZA, DOMINIC;PISE, ABHINAY C.;BHUTA, SACHIN |
分类号 |
C07D405/06 |
主分类号 |
C07D405/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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