发明名称 compostos de butirato de 4-trimetilamônio, processo para a sua preparação, composições farmacêuticas que os compreendem, método para o tratamento terapêutico ou profilático de enfermidades que são moduladas por inibidores de cpt2 e usos dos compostos
摘要 <p>This invention relates to novel 4-trimethylammoniobutyrates of the formula wherein A1, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments.</p>
申请公布号 BRPI0910591(A2) 申请公布日期 2015.09.22
申请号 BR2009PI10591 申请日期 2009.04.20
申请人 F. HOFFMANN-LA ROCHE AG. 发明人 MIRJANA ANDJELKOVIC;ODILE CHOMIENNE;PATRIZIO MATTEI;SIMONA M. CECCARELLI
分类号 C07C235/12;A61K31/197;A61K31/381;A61P3/06;A61P3/08;A61P9/12;C07C233/51;C07C237/12;C07D213/55;C07D333/24 主分类号 C07C235/12
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