| 发明名称 | Vectorization of dsRNA by cationic particles and topical use | ||
| 摘要 | The present invention relates to vectorization of double stranded RNA oligonucleotides by cationic particles chosen from among surfactant micelles, block or non-block polymer micelles, cationic liposomes and niosomes, cationic oleosomes and cationic nanoemulsions, as well as from among cationic organic or inorganic particles and nanocapsules, and topical compositions for the skin, mucous membranes or eyes. | ||
| 申请公布号 | US9139850(B2) | 申请公布日期 | 2015.09.22 |
| 申请号 | US200611436515 | 申请日期 | 2006.05.19 |
| 申请人 | L'OREAL | 发明人 | Collin-Djangone Christine;Simonnet Jean-Thierry |
| 分类号 | A61K48/00;C12N15/88;C12N15/11;C12N15/113 | 主分类号 | A61K48/00 |
| 代理机构 | Oblon, McClelland, Maier & Neustadt, L.L.P. | 代理人 | Oblon, McClelland, Maier & Neustadt, L.L.P. |
| 主权项 | 1. A composition comprising at least one double stranded RNA oligonucleotide associated with at least one cationic surfactant micelle of size less than or equal to 1 μm, having a zeta potential between 10 and 80 mV, wherein the micelle does not contain a block polymer; and at least one ingredient suitable for topical and/or ocular application. | ||
| 地址 | Paris FR | ||