发明名称 |
Methods for the treatment of uveitis with IL-1β binding antibodies |
摘要 |
Disclosed are methods and materials for inhibiting (e.g., treating or preventing) uveitis in a subject, including treatment refractory uveitis, using anti-IL-1β binding molecules (e.g., IL-1β binding antibodies or binding fragment thereof). |
申请公布号 |
US9139646(B2) |
申请公布日期 |
2015.09.22 |
申请号 |
US201314029603 |
申请日期 |
2013.09.17 |
申请人 |
XOMA (US) LLC |
发明人 |
Solinger Alan M.;Gül Ahmet |
分类号 |
A61K39/395;C07K16/24;A61K38/20;C07K16/18;A61K39/00 |
主分类号 |
A61K39/395 |
代理机构 |
Jones Day |
代理人 |
Jones Day |
主权项 |
1. A method of treating uveitis in a subject, the method comprising administering to the subject an effective amount of anti-IL-1β antibody or antigen binding fragment thereof, wherein the uveitis is treatment refractory uveitis, wherein the subject has been diagnosed with Behçet's disease, and wherein the antibody or antigen binding fragment thereof binds to human IL-1β. |
地址 |
Berkeley CA US |