发明名称 Methods for the treatment of uveitis with IL-1β binding antibodies
摘要 Disclosed are methods and materials for inhibiting (e.g., treating or preventing) uveitis in a subject, including treatment refractory uveitis, using anti-IL-1β binding molecules (e.g., IL-1β binding antibodies or binding fragment thereof).
申请公布号 US9139646(B2) 申请公布日期 2015.09.22
申请号 US201314029603 申请日期 2013.09.17
申请人 XOMA (US) LLC 发明人 Solinger Alan M.;Gül Ahmet
分类号 A61K39/395;C07K16/24;A61K38/20;C07K16/18;A61K39/00 主分类号 A61K39/395
代理机构 Jones Day 代理人 Jones Day
主权项 1. A method of treating uveitis in a subject, the method comprising administering to the subject an effective amount of anti-IL-1β antibody or antigen binding fragment thereof, wherein the uveitis is treatment refractory uveitis, wherein the subject has been diagnosed with Behçet's disease, and wherein the antibody or antigen binding fragment thereof binds to human IL-1β.
地址 Berkeley CA US