Antimicrobial agent and method for the production thereof

摘要

Provided are antimicrobial agents produced from Burkholderia cepacia complex (Bcc) bacteria, in particular from bacteria which comprise a cluster of polyketide synthesis genes. Also provided is use of the antimicrobial agents in the treatment of disease. Further provided are methods for producing antimicrobials, methods for detecting antimicrobial producing bacterial strains and kits for use in the methods.

主权项

1. A method for producing an antimicrobial agent, the method comprising:
(i) culturing a Burholderia cepaca complex (Bcc) bacterium, on minimal media comprising glycerol as the sole carbon source; (ii) allowing an antimicrobial agent to accrue; and (iii) isolating the antimicrobial agent.