| 发明名称 | Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione | ||
| 摘要 | Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of making the polymorphic forms and methods of their use are also disclosed. | ||
| 申请公布号 | US9139556(B2) | 申请公布日期 | 2015.09.22 |
| 申请号 | US201113241022 | 申请日期 | 2011.09.22 |
| 申请人 | Celgene Corporation | 发明人 | Jaworsky Markian S.;Chen Roger Shen-Chu;Muller George W.;Saindane Manohar T.;Cameron Louise M. |
| 分类号 | C07D401/04 | 主分类号 | C07D401/04 |
| 代理机构 | Jones Day | 代理人 | Jones Day |
| 主权项 | 1. A polymorphic mixture comprising less than 20% by weight amorphous 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione and greater than 80% by weight crystalline 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione dihydrate. | ||
| 地址 | Summit NJ US | ||