发明名称 SELECTIVE ANTAGONISTS OF EP4 RECEPTOR FOR CANCER TREATMENT
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to chemical and pharmaceutical industry and represents application of compound, selected from group, including 3-[2-(4-{2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]piridin-1-yl}phenyl)ethyl]-1-[(4-methylebenzene)sulphonyl]urea; 4-((1S)-1-{[5-chloro-2-(4-fluorophenoxy)benzoyl]amino}ethyl)-benzoic acid and 4-[(1S)-1-({[5-chloro-2-(3-fluorophenoxy)piridin-3-yl]carbonyl}amino)ethyl]benzoic acid, or its pharmaceutically acceptable salt for production of medication for production of cancer dimensions, associated with prostaglandin E2 (PGE2) (for instance, gastroenterologic cancer, prostate cancer, lung cancer and breast cancer) in humans or animals.EFFECT: obtaining pharmaceutically acceptable salt for production of medication for reduction of cancer dimensions.5 cl, 5 dwg, 9 ex
申请公布号 RU2563817(C2) 申请公布日期 2015.09.20
申请号 RU20110147194 申请日期 2010.04.22
申请人 RAKVALIA FARMA INK. 发明人 TAKE JUKINORI;KOIDZUMI SINITI;OKUMURA TAKAKO;NONOMURA KADZUKHIKO
分类号 A61K31/4178;A61K31/4184;A61K31/437;A61P35/00 主分类号 A61K31/4178
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