| 发明名称 |
METHOD OF PREPARING REAGENT FOR PRODUCING TECHNETIUM-99m LABELLED DOXORUBICIN |
| 摘要 |
FIELD: chemistry.SUBSTANCE: method includes preparing tin (II) chloride dihydrate solution, mixing with powdered doxorubicin hydrochloride with addition of 1 ml of a buffer solution at pH 4.01, freezing the obtained mixture at liquid nitrogen temperature, freeze drying at 50°C at pressure of 0.0015 Torr for not less than 20.5 hours, followed by final drying for not less than 5.5 hours at +16±2°C.EFFECT: invention enables to stabilise pH of the reagent for producing technetium-99m labelled doxorubicin.1 dwg |
| 申请公布号 |
RU2563134(C1) |
申请公布日期 |
2015.09.20 |
| 申请号 |
RU20140128163 |
申请日期 |
2014.07.09 |
| 申请人 |
FEDERAL'NOE GOSUDARSTVENNOE AVTONOMNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO OBRAZOVANIJA "NATSIONAL'NYJ ISSLEDOVATEL'SKIJ TOMSKIJ POLITEKHNICHESKIJ UNIVERSITET" (FGAOU VO NI TPU);FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT ONKOLOGII"SIBIRSKOGO OTDELENIJA ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK (FGBU "NII ONKOLOGII" SO RAMN);OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOST'JU "SIBNUKLON" (OOO "SIBNUKLON") |
发明人 |
SKURIDIN VIKTOR SERGEEVICH;VARLAMOVA NATAL'JA VALER'EVNA;STASJUK ELENA SERGEEVNA;NESTEROV EVGENIJ ALEKSANDROVICH;SADKIN VLADIMIR LEONIDOVICH;ROGOV ALEKSANDR SERGEEVICH;IL'INA EKATERINA ALEKSEEVNA;CHERNOV VLADIMIR IVANOVICH;SINILKIN IVAN GENNAD'EVICH;ZEL'CHAN ROMAN VLADIMIROVICH;TITSKAJA ANNA ALEKSANDROVNA |
| 分类号 |
A61K51/12;A61K31/704;A61K103/10 |
主分类号 |
A61K51/12 |
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