发明名称 METHOD FOR PREDICTION OF CLINICAL COURSE OF POST-SPLENECTOMY IMMUNE THROMBOCYTOPENIA BY SPLENIC CD8+T-LYMPHOCYTE WEIGHT
摘要 FIELD: medicine.SUBSTANCE: after splenectomy, spleen is weighed; a CD8+ T-lymphocyte count is measured morphometrically in histologic sections of a lymphoid organ after immune histochemical staining. A weight is calculated by formula: M = m × D/100%, wherein M is the CD8+ T-lymphocyte weight (g), m is the spleen weight (g), D is the CD8+ T-lymphocyte count, %. If the CD8+ T-lymphocyte value is ?9.75 g, the refractory clinical course of immune thrombocytopenia is predicted, whereas the value of <9.75 g enables stating the form of post-splenectomy immune thrombocytopenia with the favourable clinical course.EFFECT: using the given method enables predicting the clinical course of post-splenectomy immune thrombocytopenia and applying a differentiated approach to prescribing a therapy.2 ex
申请公布号 RU2563284(C1) 申请公布日期 2015.09.20
申请号 RU20140142719 申请日期 2014.10.22
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE NAUKI "KIROVSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT GEMATOLOGII I PERELIVANIJA KROVI FEDERAL'NOGO MEDIKO-BIOLOGICHESKOGO AGENTSTVA" 发明人 FEDOROVSKAJA NADEZHDA STANISLAVOVNA;D'JAKONOV DMITRIJ ANDREEVICH;FEDOROVSKAJA NINA AFANAS'EVNA;PAN'KOV VIKTOR NIKOLAEVICH
分类号 G01N33/53 主分类号 G01N33/53
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