发明名称 |
TREATMENT OF CANCER USING HYPOXIA ACTIVATED PRODRUGS |
摘要 |
Cancer can be treated by administration of a hypoxia-activated prodrug, such as TH-302, alone or in combination with other anticancer agents and/or radiation therapy. In combination therapy, the hypoxia-activated prodrug and another anticancer agent or radiation therapy may be administered within the same 24-hour period, and administration of the hypoxia-activated prodrug may be completed prior to beginning administration of the other anticancer agent or radiation therapy. |
申请公布号 |
US2015258125(A1) |
申请公布日期 |
2015.09.17 |
申请号 |
US201414574082 |
申请日期 |
2014.12.17 |
申请人 |
THRESHOLD PHARMACEUTICALS, INC. |
发明人 |
Curd John G.;Kroll Stewart;Matteucci Mark;Hart Charles P.;Duan Jian-Xin;Sun Jessica D. |
分类号 |
A61K31/675;A61K31/519;A61K31/704;A61K9/00;A61K31/7068;A61K31/555;A61K31/513;A61K31/337;A61K33/24 |
主分类号 |
A61K31/675 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
South San Francisco CA US |