发明名称 METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS
摘要 Described herein are methods of treating Parkinson's disease using arylcyclopropylamine compounds.
申请公布号 US2015258044(A1) 申请公布日期 2015.09.17
申请号 US201414513488 申请日期 2014.10.14
申请人 Duke University 发明人 McCafferty Dewey G.;Pollock Julie A.;Gooden David M.;Caron Marc G.;Gainetdinov Raul R.;Sotnikova Tatyana D.
分类号 A61K31/135;A61K31/198 主分类号 A61K31/135
代理机构 代理人
主权项 1. A method of treating Parkinson's disease in a subject in need of treatment, comprising administering to the subject an effective amount of a compound of formula (I): wherein R1, R2, R3, R4 and R5 are independently selected from hydrogen, C1-7 alkyl, C3-20 heterocyclyl, C5-20 aryl, C1-7 alkoxy, C1-7 haloalkyl, halo, amino, cyano, nitro, ether and thioether; and R6 is selected from hydrogen and optionally substituted C5-20 aryl; or an isomer, prodrug or pharmaceutically acceptable salt thereof.
地址 Durham NC US