MELATONIN-BASED FORMULATIONS FOR PARENTERAL ADMINISTRATION

摘要

The present invention relates to a melatonin formulation suitable for parenteral administration to neonates. In particular, the present invention relates to a pharmaceutical formulation comprising nanoparticles of melatonin for use for the treatment of neonatal brain injury. The formulation could be in form of powder to be reconstituted before use or in form of ready-to-use suspension in a proper aqueous vehicle. The invention is also directed to a process of its preparation and to therapeutic uses thereof.