INTRAGASTRIC VOLUME-OCCUPYING DEVICE AND METHOD FOR FABRICATING SAME

摘要

Intragastric volume-occupying devices and methods for treating obesity are provided. The devices, which are inflated by carbon dioxide, include an aluminum or silicon oxide barrier layer providing carbon dioxide retention and an alkylene vinyl alcohol polymer layer providing structural integrity in vivo.

主权项

1. An intragastric balloon system comprising a composite wall structure configured to maintain a CO2 leak rate of less than or equal to 40 cc/m2/day at 37° C., wherein the composite wall structure comprises:
a supporting film structure having a Young's Modulus of 500 Mpa or greater; a first CO2 barrier layer configured such that its CO2 barrier properties are not substantially affected by exposure to humidity levels within the gastric environment or within a central lumen of the balloon; and a second CO2 barrier layer configured such that its CO2 barrier properties are not substantially affected by mechanical forces during processing, compacting, or application of external gastric pressures.