REALTIME IMAGING AND RADIOTHERAPY OF MICROSCOPIC DISEASE

摘要

Disclosed herein are methods, systems and therapeutics concerning radiotherapy of microscopic disease based on realtime imaging. The system comprises an intra-corporeal component and an extra-corporeal component. The intra-corporeal component comprises a detector/imaging subunit and a treatment subunit, where both subunits are placed in a cavity of a patient. The extra-corporeal component comprises a detector that is placed outside any cavity of the patient. Through this system, a treatment can be applied to a target tissue in a patient concurrently or within a short period time to signal detections.

主权项

1. A tomographic imaging system for realtime imaging of sub-millimeter-sized tumor clusters in a patient, comprising:
an intra-corporeal component comprising:
i) a first detector in a cavity within the body of a patient, wherein the first detector has an imaging hemisphere;ii) a radiation source capable of emitting a therapeutic radiation, where said radiation source is also in the cavity within the body of the patient; a contrast agent, which modulates the intensity of the therapeutic radiation, and an extra-corporeal component comprising a second detector outside any cavity of the body of the patient, wherein the second detector is configured to always face the imaging hemisphere of said first detector; wherein the first detector can be rotated with respect to the body of said patient.