SYNTHETIC OLIGOSACCHARIDE SUBUNITS OF THE PSL EXOPOLYSACCHARIDE OF PSEUDOMONAS AERUGINOSA AND USES THEROF

摘要

This disclosure relates to synthetic oligosaccharide subunits of the Pseudomonas exosaccharide Psi and uses thereof, e.g, for epitope mapping of anti-Psl antibodies, for identification of anti-Psl antibodies, and for use as vaccines. In one aspect a synthetic oligosaccharide subunit of a Pseudomonas aeruginosa PsI oligosaccharide is provided, comprising the trisaccharide of formula I.