METHOD FOR PRODUCTION OF REPROGRAMMED CELL USING CHROMOSOMALLY NON-INTEGRATED VIRAL VECTOR

摘要

PROBLEM TO BE SOLVED: To provide vectors for conveniently and efficiently producing ES-like cells in which foreign genes are not integrated into the chromosome.SOLUTION: The present inventors have discovered methods for producing ES-like cells from somatic cells using chromosomally non-integrated viral vectors. Since no foreign gene is integrated into the chromosome of the produced ES-like cells, they are advantageous in tests and research, and immunological rejection and ethical problems can be avoided in disease treatments.