| 发明名称 |
THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME |
| 摘要 |
The present disclosure generally relates to nanoparticles comprising a substantially hydrophobic acid and a therapeutic agent (1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea), or pharmaceutically acceptable salts thereof, and a polymer. Other aspects include methods of making and using such nanoparticles. |
| 申请公布号 |
US2015258102(A1) |
申请公布日期 |
2015.09.17 |
| 申请号 |
US201514656899 |
申请日期 |
2015.03.13 |
| 申请人 |
Pfizer Inc. ;BIND Therapeutics, Inc. |
发明人 |
Bagrodia Shubha;Lafontaine Jennifer;Lovatt Zach;Shin Eyoung;Song Young Ho;Troiano Greg;Wang Hong |
| 分类号 |
A61K31/5377 |
主分类号 |
A61K31/5377 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A therapeutic nanoparticle of 1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea or pharmaceutically acceptable salt thereof. |
| 地址 |
New York NY US |
