发明名称 |
PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION AND TREATMENT CONTAINING PEPTIDE ORIGINATED FROM C12ORF59 PROTEIN AS AN ACTIVE INGREDIENT |
摘要 |
As explained hereinbefore, the C12orf59 gene of the present invention suppresses cancer cell invasion and inhibits cancer cell survivability, and the over expression of C12orf59 protein or a fragment thereof inhibits cancer cell invasion, so that C12orf59 gene or a fragment thereof not only can be effectively used for the pharmaceutical composition for preventing and treating cancer but also can be used as a clinical marker for screening a cancer treatment agent candidate, for diagnosing various cancers or for predicting pathological stage. In addition, the C12orf59 gene or a fragment thereof of the present invention can be used for the method for preventing and treating cancer and for the preparation of a pharmaceutical composition for preventing and treating cancer. |
申请公布号 |
US2015259385(A1) |
申请公布日期 |
2015.09.17 |
申请号 |
US201514664048 |
申请日期 |
2015.03.20 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
Kim Semi;Lee Yunhee |
分类号 |
C07K7/64;C07K7/08;A61K47/48;A61K38/10;A61K38/08;C07K7/06;A61K38/12 |
主分类号 |
C07K7/64 |
代理机构 |
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代理人 |
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主权项 |
1. An isolated anti-cancer peptide having an amino acid sequence selected from the group consisting of SEQ ID NOS: 30 to 39. |
地址 |
Daejeon KR |