发明名称 PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION AND TREATMENT CONTAINING PEPTIDE ORIGINATED FROM C12ORF59 PROTEIN AS AN ACTIVE INGREDIENT
摘要 As explained hereinbefore, the C12orf59 gene of the present invention suppresses cancer cell invasion and inhibits cancer cell survivability, and the over expression of C12orf59 protein or a fragment thereof inhibits cancer cell invasion, so that C12orf59 gene or a fragment thereof not only can be effectively used for the pharmaceutical composition for preventing and treating cancer but also can be used as a clinical marker for screening a cancer treatment agent candidate, for diagnosing various cancers or for predicting pathological stage. In addition, the C12orf59 gene or a fragment thereof of the present invention can be used for the method for preventing and treating cancer and for the preparation of a pharmaceutical composition for preventing and treating cancer.
申请公布号 US2015259385(A1) 申请公布日期 2015.09.17
申请号 US201514664048 申请日期 2015.03.20
申请人 KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY 发明人 Kim Semi;Lee Yunhee
分类号 C07K7/64;C07K7/08;A61K47/48;A61K38/10;A61K38/08;C07K7/06;A61K38/12 主分类号 C07K7/64
代理机构 代理人
主权项 1. An isolated anti-cancer peptide having an amino acid sequence selected from the group consisting of SEQ ID NOS: 30 to 39.
地址 Daejeon KR