发明名称 METHODS AND COMPOSITIONS FOR ASSESSING PATIENTS WITH NON-SMALL CELL LUNG CANCER
摘要 Methods, kits, devices, and computer systems are provided for obtaining an NSCLC marker level representation for an individual with non small cell lung carcinoma (NSCLC); and/or for providing a prognosis for an individual with NSCLC. The methods can include measuring expression levels, in a biological sample, of 2 or more NSCLC markers selected from: MAD2L1, GINS1, SLC2A1, KRT6A, FCGRT, TNIK, BCAM, KDM6A, and FAIM3; calculating an NSCLC marker level representation based on the measured expression levels; comparing the NSCLC marker level representation of the individual to a reference marker level representation; providing a prognosis based on the comparison; and/or generating a report that includes at least one of: (i) an NSCLC marker level representation, (ii) an NSCLC marker level representation and a reference NSCLC marker level representation, (iii) a prognosis, and (iv) guidance to a clinician as to a treatment recommendation based on the prognosis.
申请公布号 WO2015138769(A1) 申请公布日期 2015.09.17
申请号 WO2015US20244 申请日期 2015.03.12
申请人 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 发明人 DIEHN, MAXIMILIAN;GENTLES, ANDREW J.;ALIZADEH, ARASH ASH;BRATMAN, SCOTT VICTOR
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
主权项
地址