发明名称 COMPOSITIONS AND METHODS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS
摘要 Compositions and method are disclosed comprising ethyl icosapentate for use in treatment of non-alcoholic steatohepatitis (NASH).
申请公布号 US2015258054(A1) 申请公布日期 2015.09.17
申请号 US201214435121 申请日期 2012.10.12
申请人 MOCHIDA PHARMACEUTICAL CO., LTD. 发明人 Mizuguchi Kiyoshi;Harada Tsuyoshi;Osada Atsushi;Kawano Hiroyuki;Ichioka Masayuki
分类号 A61K31/232 主分类号 A61K31/232
代理机构 代理人
主权项 1. Ethyl icosapentate for use in the treatment or alleviation of symptoms of non-alcoholic steatohepatitis (hereinafter abbreviated as NASH) in a subject in need thereof, wherein: (a) a baseline level in a subject having NASH of at least one criteria selected from the group consisting of NAS score, steatosis score, lobular inflammation score, ballooning score and fibrosis stage is determined; and (b) an effective amount of ethyl icosapentate (EPA-E) is administered to said subject.
地址 Tokyo JP