| 发明名称 |
ANTI-LAMININ4 ANTIBODIES SPECIFIC FOR LG1-3 |
| 摘要 |
The invention provides antibodies that specifically bind to the LG1-3 modules of the G domain of laminin a4. The antibodies have the capacity to inhibit binding of laminin a4 to MCAM. The antibodies can be used for inhibiting undesired immune responses, treatment of cancer, or treatment of obesity or obesity-related diseases, among other applications. |
| 申请公布号 |
CA2938931(A1) |
申请公布日期 |
2015.09.17 |
| 申请号 |
CA20152938931 |
申请日期 |
2015.03.12 |
| 申请人 |
PROTHENA BIOSCIENCES LIMITED |
发明人 |
FLANAGAN, KENNETH;TAM, STEPHEN JED;LIU, YUE;YEDNOCK, THEODORE;BARBOUR, ROBIN |
| 分类号 |
C07K16/18;A61K39/395;A61P3/04;A61P35/00;A61P37/06;C07K16/46;C12N15/13;C12P21/08 |
主分类号 |
C07K16/18 |
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