REAL TIME NUCLEAR ISOTOPE DETECTION

摘要

A radioisotope generator that releases a daughter radioisotope from radioactive decay of a corresponding parent isotope, such as a 82Sr/82Rb radioisotope generator or 68Ge/68Ga radioisotope generator, may be used to generate radioisotopes for medical imaging applications. In some examples, a gamma ray detector is positioned to detect gamma rays emanating from radioactive eluate flowing from the generator. Based on the detected gamma rays, an activity of the daughter radioisotope in the eluate and an activity of the parent radioisotope in the eluate may be determined. Depending on the application, the activity of the daughter radioisotope and the activity of the parent radioisotope may be determined in substantially real time, e.g., so that the eluate can be diverted from patient dosing based on determined activity information for the eluate.

主权项

1. An elution system comprising:
a 82Sr/82Rb generator configured to generate 82Rb via elution with an eluant; an eluant line configured to supply the eluant to the 82Sr/82Rb generator; an eluate line configured to receive eluate eluted from the 82Sr/82Rb generator and convey the eluate to at least one of a patient line and a waste line; a gamma ray detector positioned adjacent to the eluate line and configured to detect gamma rays emitted from eluate flowing through the eluate line; and a controller communicatively coupled to the gamma ray detector and configured to receive data indicative of the gamma radiation emitted by the eluate flowing through the eluate line, determine an activity of 82Rb in the eluate based on the received data, and determine an activity of 82Sr based on the received data.