| 发明名称 |
METHOD FOR EVALUATING THE SCENT PERFORMANCE OF PERFUMES OR PERFUME MIXTURES |
| 摘要 |
Proposed is a method for evaluating the scent performance of perfumes or perfume mixtures, wherein at least one odorants is brought into contact with an olfactory receptor selected from the group consisting of OR1B1, OR2L8, OR4X2, OR4C16, OR5L1, OR8B4, OR8D2, OR10A6, OR10C1, OR12D2, OR524, OR4E2, OR4P4, OR4K2, OR4C3, OR5I1, OR10Q1 and measuring the response of the receptor. |
| 申请公布号 |
US2015260707(A1) |
申请公布日期 |
2015.09.17 |
| 申请号 |
US201414568976 |
申请日期 |
2014.12.12 |
| 申请人 |
Symrise AG |
发明人 |
Ashtibaghaei Kaveh;Gisselmann Günter;Hatt Hanns;Panten Johannes |
| 分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for evaluating the scent performance of perfumes or perfume mixtures measuring the response of the olfactory receptor, comprising the following steps:
(a) amplifying the olfactory receptors from human genomic DNA and specific primers for human olfactory receptors; (b) cloning the olfactory receptors into a pC1 expression vector including Rho-tag as a leader peptide sequence; (c) verifying the generated recombinant plasmids by sequencing; and (d) bringing at least one odorant into contact with an olfactory receptor, wherein the olfactory receptor is selected from the group consisting of OR1B1, OR2L8, OR4X2, OR4C16, OR5L1, OR8B4, OR8D2, OR10A6, OR10C1, OR12D2, OR524, OR4E2, OR4P4, OR4K2, OR4C3, OR511 and OR10Q1. |
| 地址 |
Holzminden DE |
