| 主权项 |
1. A peptide conjugate comprising:
a) a peptide which is covalently attached to a moiety which is a member selected from:in which R2 is a member selected from H, CH2OR7, COOR7 or OR7,
wherein R7 is a member selected from H, substituted or unsubstituted alkyl and substituted or unsubstituted heteroalkyl; R3, R4, R5, and R6 are members independently selected from H, substituted or unsubstituted alkyl, OR8, NHC(O)R9; wherein R8 and R9 are independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, sialic acid or polysialic acid;and wherein at least one of R3, R4, R5, R6 includes a moiety which is a member selected from:in which the indices m and n are integers independently selected from 1 to 1000;A1, A2, A3, A4, A5, A6, A7, A8, A9, A10 and A11 are members independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted hetetocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, —NA12A13, —OA12 and —SiA12A13;wherein
A12 and A13 are members independently selected from substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl. |
