The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain variable domain from a natural repertoire and a beta chain variable domain from a natural repertoire, wherein the alpha chain variable10 domain comprises a TRAV12-2 or a TRAV21 gene product and the beta chain variable domain comprises a TRBV6 gene product.
申请公布号
WO2015136072(A1)
申请公布日期
2015.09.17
申请号
WO2015EP55293
申请日期
2015.03.13
申请人
IMMUNOCORE LIMITED;ADAPTIMMUNE LIMITED
发明人
JAKOBSEN, BENT KARSTEN;MOLLOY, PETER EAMON;VUIDEPOT, ANNELISE BRIGITTE;LIDDY, NATHANIEL ROSS