Composition For Cleaving A Target DNA Comprising A Guide RNA Specific For The Target DNA And Cas Protein-Encoding Nucleic Acid Or Cas Protein, And Use Thereof

摘要

The present invention relates to targeted genome editing in eukaryotic cells or organisms. More particularly, the present invention relates to a composition for cleaving a target DNA in eukaryotic cells or organisms comprising a guide RNA specific for the target DNA and Cas 5 protein-encoding nucleic acid or Cas protein, and use thereof. WO 2014/065596 PCT1KR20131009488 [Fig. la] 0 ) ) ) U r H r - 0 H -~ H -) to UO 0 U (~-() 0 U-U H ~-~) 4,